NCT01398306

Biomarkers for Angiogenesis in Renal Cell Carcinoma and Neuro-endocrine Tumours.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 40 (actual)
• Sponsor: University Medical Center Groningen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of this study is to analyse the concentration dopamine and serotonin in thrombocytes of patients with renal cell carcinoma and neuro-endocrine tumours compared to the concentrations of these catecholamines in healthy volunteers. The concentration dopamine and serotonin in thrombocytes with and without medication will also be evaluated.

Detailed description

* To analyse the concentration catecholamines in thrombocytes of patients with clear cell renal cell carcinoma and low grade neuroendocrine tumours. * To compare these concentrations with the concentrations catecholamines in thrombocytes of healthy controls. * To analyse the concentration catecholamines in thrombocytes of patients with clear cell renal cell carcinoma and patients with low grade neuroendocrine tumours with and without medication.

Conditions

• Carcinoma
• Carcinoma, Renal Cell
• Neuroendocrine Tumors
• Carcinoid Tumor
• Pancreatic Islet Cell Tumors

Interventions

Type	Name	Description
OTHER	Blood sampling by vena punction.	We obtain 10mL blood of the patients. The blood is obtained twice: once with angiogenesis inhibitors or mTOR inhibitors, and once without.

Timeline

• Start date: 2011-07-01
• Primary completion: 2012-04-01
• Completion: 2012-04-01
• First posted: 2011-07-20
• Last updated: 2024-05-06

Locations

1 site across 1 country: Netherlands