NCT01394380

Reduction of Sweetened Beverages and Intrahepatic Fat

Effects of a Reduction of Sweetened Beverages Consumption in Overweight High Consumers on Cardiometabolic Risk Factors

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: University of Lausanne · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The study will enroll 68 overweight male and female subjects with a high (\> 2 3dl-can soda/day) consumption of sweetened beverage per day. After a run-in period of 4 weeks, subjects will be randomized to either a 12-week intervention arm in which sweetened beverages will be replaced by artificially sweetened, calorie-free beverages, or to a control arm. The following measurements will be performed at the end of the run-in period and at the end of the intervention period * intrahepatic fat concentration * visceral fat volume * changes in day-long metabolic profile from baseline(plasma glucose, insulin, and triglyceride concentrations) * changes in food intake and daily energy, carbohydrate and sugars intake from baseline

Conditions

• Obesity
• Dyslipidemia
• Metabolic Syndrome

Interventions

Type	Name	Description
OTHER	artificially sweetened sodas	subjects will be allowed unlimited consumption of calorie-free, artificially-sweetened sodas, water, tea or coffee

Timeline

• Start date: 2011-10-01
• Primary completion: 2014-04-01
• Completion: 2014-04-01
• First posted: 2011-07-14
• Last updated: 2014-06-04

Locations

1 site across 1 country: Switzerland