NCT01389791

MgSO4 Combined With Rocuronium Priming

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Seoul National University Bundang Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Priming with either rocuronium or MgSO4 is known to accelerate the effect of rocuronium on muscle relaxation. The purpose of this study is to define the effect of MgSO4 on the rocuronium-priming.

Detailed description

Acceleration of muscle relaxation is beneficial in rapid-sequence intubation. If MgSO4 combined with priming is efficient in accelerating muscle relaxation, it would be an interesting alternative to rapid-sequence intubation.

Conditions

• Muscle Relaxation

Interventions

Type	Name	Description
DRUG	magnesium sulfate	Patients in this group receive intravenous MgSO4 50mg/kg before administration of rocuronium (induction dose).
DRUG	priming	Patients in this group receive 0.06mg/kg of rocuronium before administration of 0.54mg/kg of rocuronium.
DRUG	magnesium sulfate and priming	Patients in this group receive MgSO4 50mg/kg and 0.06mg/kg of rocuronium before administration of 0.54mg/kg of rocuronium.

Timeline

• Start date: 2011-05-01
• Primary completion: 2012-01-01
• Completion: 2012-01-01
• First posted: 2011-07-08
• Last updated: 2012-01-10

Locations

1 site across 1 country: South Korea