NCT01388738

Navigation Brain Stimulation for Evaluation of the Neuroprotective Drug Efficiency in Patients After Ischemic Stroke.

Navigation Brain Stimulation (NBS) for Evaluation of the Neuroprotective Drug Efficiency in Patients After Ischemic Stroke.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Clinical Institute of the Brain, Russia · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Ischemic stroke (IS) causes high mortality and severe disability. To improve outcome it's very important to choose the right way of the management of the patient and an appropriate drugs. There is a large number of the so-called neuroprotective drugs, which were effective in laboratory, but didn't show positive results in clinical studies with using traditional clinical scales scores as a primary outcome measures. Specialists suggest, that the investigators could receive better results if the investigators change design of the studies, particularly if the investigators select more precise and sensitive method of assessment. Aim of this study: to determine the role of navigated brain stimulation (NBS) for evaluation of the changes in the motor centers and motor tracts after administration of different cerebroprotective drugs. (The substances won't be compared to each other).

Conditions

• Stroke

Interventions

Type	Name	Description
DRUG	citicoline	citicoline IV 2000 mg, then citicoline 900 mg/day (300mg\*3 times per day) per os
DRUG	L-Alpha glycerylphosphorylcholine	choline alfoscerate IV 1000mg daily 10 days
DRUG	cerebrolysin	Cerebrolysin IV 10 ml daily 10 days

Timeline

• Start date: 2011-01-01
• Primary completion: 2011-10-01
• Completion: 2011-11-01
• First posted: 2011-07-07
• Last updated: 2011-12-23

Locations

1 site across 1 country: Russia