NCT01382303

Effect of Pentoxifylline on Proteinuria in Korean Type 2 Diabetic Patients

Effect of Pentoxifylline on Proteinuria in Korean Type 2 Diabetic Patients : Prospective, Randomized, Double Blinded Active Control, Multicenter Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 174 (actual)
• Sponsor: Ajou University School of Medicine · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This multi-center, randomized controlled study aims to evaluate the effects of pentoxifylline on proteinuria in Korean type 2 diabetic patients.

Detailed description

The investigators will recruit adults patients with type 2 diabetes aged over 20 years with spot urine albumin to creatinine ratio over 30mg/g in two consecutive measurements. Enrolled patients will be randomly assigned to receive pentoxifylline (400mg three times daily) or placebo for 24 weeks. Fasting blood and spot urine will be collected at baseline, 12 weeks and 24 weeks. The investigators will evaluate the impact of pentoxifylline on proteinuria in type 2 diabetic patients.

Conditions

• Type 2 Diabetes

Interventions

Type	Name	Description
DRUG	Pentoxifylline	Pentoxifylline 400mg three times a day
DRUG	Placebo	placebo tablet three times a day

Timeline

• Start date: 2010-10-25
• Primary completion: 2013-12-20
• Completion: 2013-12-20
• First posted: 2011-06-27
• Last updated: 2017-06-16
• Results posted: 2017-06-16

Locations

1 site across 1 country: South Korea