Clinical Trials Directory

Trials / Terminated

TerminatedNCT01381731

A Double-masked, Randomized, Placebo-controlled,Pilot Study of Diquafosol Tetrasodium in Subjects Following Photorefractive Keratectomy (PRK)

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
14 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
18 Years – 45 Years
Healthy volunteers
Not accepted

Summary

The objectives of this trial are to: * Assess the safety and tolerability of diquafosol tetrasodium ophthalmic solution versus placebo following one week of treatment in subjects undergoing photorefractive keratectomy (PRK). * Evaluate the potential of diquafosol to accelerate corneal wound healing/re-epithelialization following PRK.

Conditions

Interventions

TypeNameDescription
DRUGdiquafosol tetrasodium ophthalmic solution 2%opthalmic solution 2 drops in each eye QID
DRUGplaceboopthalmic solution 2 drops in each eye QID

Timeline

Start date
2005-04-01
Primary completion
2005-06-01
Completion
2005-06-01
First posted
2011-06-27
Last updated
2015-11-25

Source: ClinicalTrials.gov record NCT01381731. Inclusion in this directory is not an endorsement.