NCT01381081

Platelet-rich Plasma Intra-articular Knee Injections for Knee Osteoarthritis

A Prospective, Randomized, Double-blinded, Clinical Trial, Comparing Platelet-rich Plasma Intra-articular Knee Injections Versus Corticosteroid Intra-articular Knee Injections for Knee Osteoarthritis

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 74 (actual)
• Sponsor: Hospital Universitari Vall d'Hebron Research Institute · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The benefit of using platelet rich plasma (PRP) in cartilage injuries, and specifically in degenerative ones, has not been assessed yet. Current studies on the PRP healing or repairing effect on knee cartilage degenerative injuries are not conclusive to establish a standard of behavior, although PRP has shown to improve joint functionality and reduce pain. Hypothesis: PRP intra-articular injections in osteoarthritic knees reduces pain and leads to a more effective and lasting functional recovering than corticosteroid intra-articular injections.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
BIOLOGICAL	platelet-rich plasma	a single intra-articular injection
DRUG	Corticosteroid	A single betamethasone and bupivacaine intra-articular injection

Timeline

• Start date: 2011-07-01
• Primary completion: 2014-01-01
• Completion: 2014-01-01
• First posted: 2011-06-27
• Last updated: 2015-02-24

Locations

1 site across 1 country: Spain