Clinical Trials Directory

Trials / Terminated

TerminatedNCT01377909

HCV Treatment With Fluvastatin, Simvastatin to Improve Interferon Sensitivity

An Investigator-initiated Pilot Study Using Statins to Improve the Anti-HCV Response to Peginterferon Alfa 2-b and Ribavirin in Previous Non-responders

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
20 (actual)
Sponsor
Bader, Ted, M.D. · Individual
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Objective: The goal is to improve peginterferon sensitivity in previous poor responders. "Sensitivity" here means the host's ability to kill more HCV. Design: Twenty poor responders to prior PIFN/RBV will be given 48 weeks of statin monotherapy. Veterans and civilians between the ages of 18 and 70 are eligible.

Conditions

Interventions

TypeNameDescription
DRUGstatindaily statin orally for 48 weeks

Timeline

Start date
2012-03-01
Primary completion
2013-08-01
Completion
2013-08-01
First posted
2011-06-22
Last updated
2013-08-22

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01377909. Inclusion in this directory is not an endorsement.