NCT01375348

Relationship Between Cognitive Function and Pain

Cognitive Function in Healthy Volunteers Exposed to Acute Pain Before and After Administration of Remifentanil

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: University of Aarhus · Academic / Other
• Sex: Male
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Patients with chronic pain can experience considerable changes in their cognitive function such as forgetfulness, increased absentmindedness, confusion etc. Opioids (e.g. morphine and morphine-like analgesics) are often used in treatment of acute and chronic pain and can lead to worsening of the cognitive function. The interaction between pain, treatment and cognitive function is very complex and is far from understood. The hypothesis of the present study is that by use of experimental pain in healthy volunteers it will be possible to elucidate the interaction between pain, treatment and cognitive function.

Conditions

• Cognitive Ability, General

Interventions

Type	Name	Description
DRUG	Ultiva (remifentanil) or placebo	0.1microg/kg/min remifentanil administered as infusion Max infusion time is 20min

Timeline

• Start date: 2011-06-01
• Primary completion: 2012-02-01
• Completion: 2012-02-01
• First posted: 2011-06-17
• Last updated: 2012-02-14

Locations

1 site across 1 country: Denmark