Clinical Trials Directory

Trials / Completed

CompletedNCT01371331

A Study to Determine Pharmacokinetics of Children Receiving Modigraf (Tacrolimus Granules) Following Solid Organ Transplantation

A Multicentre, Open-label, Pharmacokinetic Study of Modigraf® (Tacrolimus Granules) in de Novo Paediatric Allograft Recipients

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
52 (actual)
Sponsor
Astellas Pharma Europe Ltd. · Industry
Sex
All
Age
0 Years – 12 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to find out how much of Modigraf is absorbed and used in the body and how fast it leaves the body (Pharmacokinetics). The results will then help to decide how much Modigraf in future can be given safely to children and young people following transplantation.

Detailed description

The primary objective of this study is to determine the pharmacokinetics (PK) of tacrolimus following oral administration of Modigraf, after the first oral dose and at steady state in paediatric subjects undergoing de novo allograft transplantation.

Conditions

Interventions

TypeNameDescription
DRUGTacrolimus granulesoral

Timeline

Start date
2011-06-09
Primary completion
2015-02-03
Completion
2015-02-03
First posted
2011-06-10
Last updated
2024-11-01

Locations

10 sites across 6 countries: Belgium, France, Germany, Poland, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT01371331. Inclusion in this directory is not an endorsement.