NCT01370200

Regional Citrate Anticoagulation in Plasma Exchange Treatment

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 140 (actual)
• Sponsor: University Medical Centre Ljubljana · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators want to compare the efficacy of plasma exchange treatment with using two different citrates ( 4% and 15% ) as anticoagulants in plasma exchange treatment. The efficacy of plasma exchange treatment is better with using 15% trisodium citrate as anticoagulant during the plasma exchange procedure.

Detailed description

To compare the elimination rate of immunoglobulins in plasma exchange treatment by using two differently concentrated citrates for anticoagulation during plasma exchange procedure. At the same time we want to compare acid-base , electrolyte status and anticoagulation protocol in two citrate groups.

Conditions

• Focal Segmental Glomerulosclerosis
• Guillain-Barre Syndrome

Interventions

Type	Name	Description
PROCEDURE	plasma exchange treatment	the therapeutic plasma exchange is the procedure of removing the plasma of the patient including pathological macromolecules and replacing it with the replacement fluid

Timeline

• Start date: 2011-04-01
• Primary completion: 2014-12-01
• Completion: 2014-12-01
• First posted: 2011-06-09
• Last updated: 2015-05-27

Locations

1 site across 1 country: Slovenia