NCT01369043

The Effects of Vitamin E and Vitamin C and Exercise

Modulation of Insulin and Exercise Responses by Vitamin E and Vitamin C

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 1 (actual)
• Sponsor: USDA Grand Forks Human Nutrition Research Center · Federal
• Sex: All
• Age: 30 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Moderate exercise is thought to be one of the best known means to improve how insulin works in people. Taking vitamin C and vitamin E is also thought to have the same effect. This study is being done to see if taking vitamin C and vitamin E improves or hinders how insulin works when people do not exercise and when they do exercise.

Detailed description

The objective of the study is to determine in humans whether anti-oxidant supplementation with ascorbate (vitamin C) or R,R,R-α-tocopherol acetate (vitamin E) improves insulin sensitivity in the untrained state but blocks exercise-induced increases in insulin sensitivity and other adaptations to exercise. The results will provide new information on the roles of anti-oxidant supplementation in modifying insulin sensitivity, and will inform guidelines for anti-oxidant supplementation as an adjunct to exercise.

Conditions

• Exercise and Non-exercise Effect Upon Vitamins E and C

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Vitamin E and Vitamin C	Vitamin E 400 iu/dose daily times 56 days Vitamin C 500 mg/dose twice daily times 56 days

Timeline

• Start date: 2011-05-01
• Primary completion: 2012-03-01
• Completion: 2012-03-01
• First posted: 2011-06-08
• Last updated: 2015-03-09

Locations

1 site across 1 country: United States