Clinical Trials Directory

Trials / Completed

CompletedNCT01368276

An Extended Use Study of Safety and Efficacy of Talimogene Laherparepvec in Melanoma

An Extension Protocol to Evaluate the Efficacy and Safety of Extended Use Treatment With OncoVEX^GM-CSF for Eligible Melanoma Patients Participating in Study 005/05

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
31 (actual)
Sponsor
BioVex Limited · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to learn about the safety and the risks of using talimogene laherparepvec in patients who already received treatment with talimogene laherparepvec in study 005/05 (NCT00769704), and to see if extended treatment with talimogene laherparepvec can destroy melanoma tumors.

Conditions

Interventions

TypeNameDescription
BIOLOGICALTalimogene LaherparepvecUp to 4 mL of 10⁸ pfu/mL/per intratumoral injection
DRUGGranulocyte Macrophage Colony-Stimulating Factor (GM-CSF)125 µg/m² subcutaneous injection

Timeline

Start date
2010-10-01
Primary completion
2014-09-01
Completion
2014-09-01
First posted
2011-06-07
Last updated
2015-12-18
Results posted
2015-12-18

Locations

10 sites across 2 countries: United States, United Kingdom

Source: ClinicalTrials.gov record NCT01368276. Inclusion in this directory is not an endorsement.

An Extended Use Study of Safety and Efficacy of Talimogene Laherparepvec in Melanoma (NCT01368276) · Clinical Trials Directory