NCT01367197

Study of the Effect of Exercise Training on Patients in Atrial Fibrillation

Randomised Study of the Effect of Exercise Training on Patients in Atrial Fibrillation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 49 (actual)
• Sponsor: Copenhagen University Hospital, Hvidovre · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

PURPOSE Physical exercise is beneficial for patients with ischemic heart disease and chronic heart failure, while little is known about the effect in atrial fibrillation (AF). The investigators studied the effect of physical exercise on cardiac output (CO), max. exercise capacity, biomarkers and quality of life (Qol) in patients with AF in a randomised study of physical exercise training three times weekly for twelve weeks. HYPOTHESIS Exercise training improves cardiac output (CO), max. exercise capacity, biomarkers and quality of life (Qol) in patients with AF. METHODS Assessment of exercise capacity, CO, Qol, body composition, six minute walk test and muscular strength was performed before and after 12 weeks. Resting echocardiography was done at baseline. CO was measured using impedance cardiography at rest and during maximal exercise testing on an ergometer bicycle. Body composition, muscular strength and six minutes walking capacity were measured before and after the training period. Qol was evaluated by the use of the standardized validated questionnaires Short Form 36 (SF-36) and the Minnesota Living with Heart Failure Questionnaire (MLHF-Q). Training consisted of aerobic exercise at 70 percent of max. capacity estimated by Borg-scale.

Conditions

• Atrial Fibrillation

Interventions

Type	Name	Description
BEHAVIORAL	exercise training	group based exercise training

Timeline

• Start date: 2009-01-01
• Primary completion: 2010-12-01
• Completion: 2011-06-01
• First posted: 2011-06-07
• Last updated: 2011-06-07

Locations

1 site across 1 country: Denmark