NCT01366885

Vitamin D to Prevent Autism in Newborn Siblings

Study of Vitamin D to Prevent Autism in Newborn Siblings

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Oregon Health and Science University · Academic / Other
• Sex: Female
• Age: 20 Years – 44 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether by administering vitamin D to mothers who already have at least one child with autism and who are pregnant, that the vitamin D will prevent the recurrence of autism in the newborn sibling.

Detailed description

The incidence of autism is increasing. Also, women of childbearing age are increasingly found to be insufficient/deficient in vitamin D. Vitamin D is a neurohormone which is important for development of the child, especially of the child's brain. The primary source of vitamin D is from the sun through one's skin. People have been avoiding the sun because of skin cancer, because of increasing Television watching, computer viewing and wearing clothes that cover most of the body. This approach will study whether making the pregnant mother, whose child is at risk for autism because of a previous child with autism, replete with vitamin D will prevent that recurrence of autism in the newborn sibling.

Conditions

• Autistic Disorder

Interventions

Type	Name	Description
DRUG	Vitamin D3	5000 IU D3 capsule oral/day for entire pregnancy. 7000 IU D3/day during breastfeeding. If not breast feeding, baby gets 400 IU D3/day. Baby increased to 1000 IU D3/day at one year of age.

Timeline

• Start date: 2008-02-01
• Primary completion: 2016-02-01
• Completion: 2016-02-01
• First posted: 2011-06-06
• Last updated: 2016-06-14
• Results posted: 2016-06-14

Locations

1 site across 1 country: United States