Trials / Completed
CompletedNCT01366378
Effect of Cimetidine on the Single-Dose PK of IV- Administered MNTX
A Phase 1, Open-Label, Study of the Effect of Cimetidine, a Known Inhibitor of Active Renal Secretion, on the Single-Dose Pharmacokinetics of Intravenously-Administered Methylnaltrexone in Healthy Adults
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 18 (actual)
- Sponsor
- Bausch Health Americas, Inc. · Industry
- Sex
- All
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
This open-label study assesses the single-dose pharmacokinetics of intravenously-administered MNTX in healthy adult male and female subjects in the absence of, and in the presence of, orally-administered cimetidine.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | methylnaltrexone |
Timeline
- Start date
- 2007-01-01
- Primary completion
- 2007-02-01
- Completion
- 2007-02-01
- First posted
- 2011-06-06
- Last updated
- 2019-11-27
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01366378. Inclusion in this directory is not an endorsement.