Clinical Trials Directory

Trials / Unknown

UnknownNCT01363739

Evaluation of VEGF Polymorphism as Predictive Factor in Metastatic Colorectal Cancer Treated With Folfiri Plus Bevacizumab

Prospective Evaluation of -1498 c/t VEGF Polymorphism in the Prediction of Benefit From First-line Folfiri Plus Bevacizumab in Metastatic Colorectal Cancer Patients

Status
Unknown
Phase
Study type
Observational
Enrollment
265 (estimated)
Sponsor
Azienda Ospedaliero, Universitaria Pisana · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

-1498C/T VEGF polymorphism, as suggested by a recent retrospective analysis, seems to have a role in predicting the efficacy of Bevacizumab plus FOLFIRI in first-line treatment of metastatic colorectal cancer patients. The present study aims to prospectively evaluate the predictive role of this polymorphism in metastatic colorectal patients receiving the same treatment.

Conditions

Timeline

Start date
2009-04-01
First posted
2011-06-02
Last updated
2011-06-02

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT01363739. Inclusion in this directory is not an endorsement.