Clinical Trials Directory

Trials / Completed

CompletedNCT01363440

Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Patients With Diabetic Macular Edema

A Double-Masked, Randomized, Active-Controlled, Phase 3 Study of the Efficacy and Safety of Intravitreal Administration of VEGF Trap-Eye in Patients With Diabetic Macular Edema

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
466 (actual)
Sponsor
Regeneron Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the efficacy of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) on the best corrected visual acuity (BCVA) assessed by the early treatment diabetic retinopathy study (ETDRS) chart in patients with diabetic macular edema (DME) with central involvement.

Conditions

Interventions

TypeNameDescription
DRUGIntravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321)
PROCEDUREMacular Laser PhotocoagulationLaser therapy

Timeline

Start date
2011-05-01
Primary completion
2013-01-01
Completion
2014-11-01
First posted
2011-06-01
Last updated
2016-05-30
Results posted
2015-04-20

Locations

51 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01363440. Inclusion in this directory is not an endorsement.