Trials / Completed
CompletedNCT01361828
Optic Nerve and Retinal Functions With Bevacizumab
Electrophysiological Assessment of Optic Nerve and Retinal Functions Following Intravitreal Injection of Bevacizumab (Avastin).
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 45 (actual)
- Sponsor
- Cairo University · Academic / Other
- Sex
- All
- Age
- 24 Years – 62 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to investigate the possible affection of optic nerve and retinal functions following intravitreal bevacizumab injection in human eyes.
Detailed description
To evaluate the retinal and optic nerve functions of bevacizumab when injected intravitreal in human eyes using electrophysiological tests; Electroretinogram (ERG) and Visual Evoked Potentials (VEP). Forty five eyes of 45 patients with choroidal neovascular membrane (CNV) who were prepared for intravitreal injections of 1.25mg bevacizumab underwent baseline ERG and VEP in both eyes before, and at 1 and 4 weeks after the intravitreal injections.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Electrophysiology | Visual Evoked Potential and Elctroretinogram |
Timeline
- Start date
- 2010-01-01
- Primary completion
- 2010-07-01
- Completion
- 2010-07-01
- First posted
- 2011-05-27
- Last updated
- 2011-05-27
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT01361828. Inclusion in this directory is not an endorsement.