NCT01360918

Concomitant Epicardial Pulmonary Vein Isolation in Patients With Atrial Fibrillation Undergoing Elective Cardiac Surgery

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 2 (actual)
• Sponsor: Medisch Spectrum Twente · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Recent studies demonstrated that radiofrequency isolation of the pulmonary veins (PVI) is a superior alternative to antiarrhythmic drug therapy in patients with symptomatical paroxysmal atrial fibrillation (AF). A substantial proportion of patients undergoing elective cardiac surgery also suffer from atrial fibrillation. No evidence exists if epicardial PVI is beneficial in patients with a history of AF undergoing coronary bypass surgery (CABG) for the concomitant treatment of AF. The investigators aim to establish the effectiveness of incorporating epicardial pulmonary vein isolation into elective cardiac surgery.

Conditions

• Atrial Fibrillation

Interventions

Type	Name	Description
DEVICE	Epicardial pulmonary vein isolation	After the CABG procedure, a bilateral epicardial pulmonary vein isolation is performed under general anaesthesia and double-lumen endotracheal ventilation.
OTHER	Usual care	Management of atrial fibrillation according to current guidelines using rate control pharmacological therapy.

Timeline

• Start date: 2011-05-01
• Primary completion: 2013-05-01
• Completion: 2014-05-01
• First posted: 2011-05-26
• Last updated: 2016-07-07

Locations

1 site across 1 country: Netherlands