Clinical Trials Directory

Trials / Completed

CompletedNCT01358175

16 Week Efficacy and 2 Year Long Term Safety and Efficacy of Secukinumab in Patients With Active Ankylosing Spondylitis

A Randomized, Double-blind, Placebo-controlled, Multicenter Study of Secukinumab to Demonstrate the 16 Week Efficacy and to Assess the Long Term Safety, Tolerability and Efficacy up to 2 Years in Patients With Active Ankylosing Spondylitis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
371 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study will assess the efficacy and safety of secukinumab in patients with active ankylosing spondylitis who are intolerant to or have had an inadequate response to NSAIDs, DMARDs and / or TNFα inhibitor therapy.

Conditions

Interventions

TypeNameDescription
DRUGSecukinumab (75 mg)Secukinumab (75 mg)
DRUGSecukinumab (150 mg)Secukinumab (150 mg)
DRUGPlaceboPlacebo

Timeline

Start date
2011-10-01
Primary completion
2014-12-01
Completion
2014-12-01
First posted
2011-05-23
Last updated
2017-03-09
Results posted
2017-01-27

Locations

67 sites across 14 countries: United States, Belgium, Bulgaria, Canada, France, Germany, Italy, Mexico, Netherlands, Peru, Russia, Taiwan, Turkey (Türkiye), United Kingdom

Source: ClinicalTrials.gov record NCT01358175. Inclusion in this directory is not an endorsement.