NCT01356693

Bromelin, a Compound Prepared With Ananas Comocus Extract and Honey, for Acute Cough

Randomized,Double-blind, Placebo Controlled Clinical Trial to Evaluate the Efficacy of the Phytotherapic Compound "Bromelin" on Acute Irritative Cough

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 102 (estimated)
• Sponsor: Universidade Federal de Pernambuco · Academic / Other
• Sex: All
• Age: 2 Years – 15 Years
• Healthy volunteers: Not accepted

Summary

Cough is the most bothersome symptom for patients with the common cold. The objective of the study is to compare the phytotherapic "Bromelin", a compound preparation of honey from the bee apis mellifera with the extract of the pineapple (Ananas comosus) with placebo in reducing cough episodes in patients with the common cold.

Detailed description

Common cold is very frequent and cough is one of the most troublesome symptoms. Over-the-counter medications are used by patients without prescription, many times with important side effects. Bromelin, a compound made with honey and pineapple extract could offer cough symptomatic relief as a soothing agent. This study aims to compare this compound with placebo in reducing cough in patients with common cold in an clinical trial designed in conformity to CONSORT guidelines.

Conditions

• Cough, Acute

Interventions

Type	Name	Description
DRUG	Bromelin	Ananas comosus extract (3,3g) on vehicle: methylparaben, propylparaben, honey from Apis mellifera, sodium benzoate, ethilic alcohol, water) 5ml. Given in single dose.
DRUG	Placebo	Placebo with mimicking characteristics of experimental drug

Timeline

• Start date: 2011-06-01
• Primary completion: 2011-11-01
• Completion: 2012-03-01
• First posted: 2011-05-19
• Last updated: 2011-06-28

Locations

1 site across 1 country: Brazil