Trials / Unknown
UnknownNCT01355055
Sympathetic Activity and Renal Denervation
Influences of Catheter-based Renal Denervation on Central Sympathetic Nervous System Regulation in Refractory Hypertension
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 26 (estimated)
- Sponsor
- Hannover Medical School · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Primary hypothesis: Catheter-based renal denervation reduces central sympathetic activation in patients with refractory hypertension. Secondary hypotheses: 1. The magnitude of the individual depressor response after catheter-based renal denervation depends on the extent of sympathoinhibition. 2. Both, the reduction in arterial pressure and in central sympathetic activation are sustained over time up to 24±3 months after catheter-based renal denervation. 3. Catheter-based renal denervation resets the sympathetic baroreflex to lower blood pressure values.
Conditions
Timeline
- Start date
- 2011-03-01
- First posted
- 2011-05-17
- Last updated
- 2011-05-17
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT01355055. Inclusion in this directory is not an endorsement.