NCT01354626

Dietary Protein and Hepatic Fat Accumulation

Influence of Increasing Dietary Protein on Hepatic Fat Accumulation and Postprandial Metabolism

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: Wageningen University · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to investigate the potential beneficial effect of increasing protein in the diet in order to decrease hepatic lipid accumulation on a high-fat diet. The investigators hypothesize that increasing protein in a high-fat diet suppresses lipid accumulation in the liver, and that changes in (hepatic) fat handling underlie this reduced lipid accumulation.

Conditions

• Hepatic Fat Accumulation
• Nonalcoholic Fatty Liver Disease

Interventions

Type	Name	Description
OTHER	dietary protein	in the low-protein group 13EN% of protein will be provided in the diet; in the high-protein 25EN% of protein will be provided
OTHER	low-protein	The control group will get a diet which is according to healthy eating guidelines.

Timeline

• Start date: 2011-08-01
• Primary completion: 2012-03-01
• Completion: 2012-03-01
• First posted: 2011-05-17
• Last updated: 2012-03-15

Locations

1 site across 1 country: Netherlands