Clinical Trials Directory

Trials / Completed

CompletedNCT01354418

Bioequivalence of Single Dose Phenylephrine Extended Release Tablets and Phenylephrine HCl Immediate Release Tablets Dosed Every Four Hours (P08340)(COMPLETED)

A Randomized Crossover Bioequivalence Study Comparing a Single Dose of Phenylephrine HCl 30 mg Extended Release Tablet to Three Phenylephrine HCl 10 mg Immediate Release Tablets Each Consecutively Dosed Four Hours Apart Under Fed and Fasting Conditions

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
24 (actual)
Sponsor
Bayer · Industry
Sex
All
Age
18 Years – 45 Years
Healthy volunteers
Accepted

Summary

This study will assess the food-effect bioavailability of an extended release formulation of phenylephrine HCl and its bioequivalence to the marketed immediate release phenylephrine HCl product.

Conditions

Interventions

TypeNameDescription
DRUGPhenylephrine HCl Extended ReleaseOne phenylephrine HCl 30 mg extended release tablet orally
DRUGPhenylephrine HCl Immediate ReleaseOne phenylephrine HCl 10 mg immediate release tablet every 4 hours for three doses

Timeline

Start date
2011-05-01
Primary completion
2011-06-01
Completion
2011-07-01
First posted
2011-05-16
Last updated
2015-02-23

Source: ClinicalTrials.gov record NCT01354418. Inclusion in this directory is not an endorsement.