NCT01354275

In Vitro Fertilization Outcomes of Two Treatment Protocols in Women With Polycystic Ovary Syndrome

IVF/ICSI Outcomes of OCP Plus GnRH Agonist Protocol Versus OCP Plus GnRH Antagonist Fixed Protocol in Women With PCOS

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (actual)
• Sponsor: Bulent Haydardedeoglu · Academic / Other
• Sex: Female
• Age: 20 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Outcomes of IVF/ICSI cycles of women with PCOS undergoing Gonadotropin Releasing Hormone (GnRH) agonist and GnRH Antagonist fixed protocol.

Detailed description

Women with PCOS undergoing IVF/ICSI cycles will be evaluated by two different protocols. One arm of the study includes oral contraceptive plus GnRH agonist protocol with 150 IU FSH (standard dose) and second arm includes oral contraceptive plus GnRH Antagonist with 150 IU FSH dose and fixed 6th day starting of GnRH Antagonist.

Conditions

• PCOS GnRH Antagonist and GnRH Agonist IVF/ICSI Cycles

Interventions

Type	Name	Description
OTHER	To compare the IVF/ICSI outcomes of GnRH Antagonist cycle versus GnRH agonist cycle	150 IU FSH dose and OCP plus GnRH Agonist (long luteal) IVF/ICSI cycle and 150 IU FSH dose and OCP plus GnRH Antagonist (Fixed protocol) IVF/ICSI Cycle
OTHER	GnRH Antagonist	GnRH Antagonist cycle; 150 IU FSH and sixth day Antagonist will be administered

Timeline

• Start date: 2009-03-01
• Primary completion: 2011-03-01
• Completion: 2011-06-01
• First posted: 2011-05-16
• Last updated: 2012-02-03

Locations

1 site across 1 country: Turkey (Türkiye)