NCT01354145

Study of the Effect of Chondroitin Sulfate on Structural Changes in Knee Osteoarthritis Patients Assessed by MRI

Twenty-four Month Exploratory Study of the Effect of Chondroitin Sulphate on Structural Changes in Knee Osteoarthritis Patients as Assessed by MRI

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 194 (actual)
• Sponsor: Bioiberica · Industry
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

The main purpose of this study is to compare the cartilage volume loss at the Baseline visit and after 24 months of treatment in patients treated with CHONDROITIN SULPHATE (CONDROSAN) 1200 mg daily vs. patients treated with CELECOXIB 200 mg daily.

Detailed description

To compare long term disease modifiying and symptomatic effects at the Baseline visit and after 24 months of treatment in patients treated with CHONDROITIN SULPHATE 1200 mg daily vs. patients treated with CELECOXIB 200 mg daily.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
DRUG	Chondroitin sulfate	Chondroitin sulphate 1200 mg/day, 24 months treatment period
DRUG	Celecoxib	Celecoxib 200 mg/day, 24 months treatment period

Timeline

• Start date: 2011-06-01
• Primary completion: 2014-09-01
• Completion: 2014-10-01
• First posted: 2011-05-16
• Last updated: 2016-08-19
• Results posted: 2016-08-19

Locations

5 sites across 1 country: Canada