NCT01353807

Impact of Fish Oil Supplementation in 3rd Trimester of Pregnancy on Maternal and Offspring Health

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 533 (actual)
• Sponsor: Centre for Fetal Programming, Denmark · Academic / Other
• Sex: Female
• Age: 20 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The aim of the trial is to investigate the effect of daily supplementation with 2.7 grams of long chain n-3 fatty acids during the third trimester of pregnancy. In 1990, 533 pregnant women, while they were in gestational week 30, were randomized to fish oil supplements providing the mentioned amount of long chain n-3 fatty acids, olive oil supplements, or no supplements; they were asked to take the supplements until delivery. Health outcomes were assessed during pregnancy and delivery. Further, offspring health and development has been examined during the ensuring two decades by making linkages to the rich Danish health and administrative registries, by asking the offspring to complete web-based questionnaires, and by examining the offspring physically.

Conditions

• Preterm Delivery
• Atopy
• Metabolic Syndrome

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Fish oil	4 1-g gelatine capsules per day providing 2,7 grams long chain n-3 fatty acids
DIETARY_SUPPLEMENT	Olive oil	4 1-g gelatine capsules with virgin olive oil

Timeline

• Start date: 1989-11-01
• Primary completion: 1990-12-01
• Completion: 2011-05-01
• First posted: 2011-05-16
• Last updated: 2014-02-28

Locations

1 site across 1 country: Denmark