NCT01353144

A Comparison of Two Therapeutic Strategies for the Treatment of Aspirin-associated Peptic Ulcers

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 178 (actual)
• Sponsor: Kaohsiung Veterans General Hospital. · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Esomeprazole plus aspirin compared with esomeprazole alone for the treatment of aspirin-related peptic ulcers.

Detailed description

The aims of this study are to compare esomeprazole plus aspirin with esomeprazole alone in the treatment of aspirin-related ulcers. Patients with aspirin-related peptic ulcers are randomized to receive esomeprazole (40 mg/day) plus aspirin (100 mg/day) or esomeprazole (40 mg/day) alone for 8 weeks. Follow-up endoscopy was carried out at the end of the eighth week. The primary end point was the healing of peptic ulcers.

Conditions

• Peptic Ulcer

Interventions

Type	Name	Description
DRUG	aspirin	aspirin, 100 mg, qd x 8 weeks

Timeline

• Start date: 2007-06-01
• Primary completion: 2008-05-01
• Completion: 2008-05-01
• First posted: 2011-05-12
• Last updated: 2016-11-01
• Results posted: 2015-10-14

Locations

3 sites across 1 country: Taiwan