NCT01350921

Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

A Sequential, Open Label Study to Compare the Pharmacokinetics, Safety and Tolerability of Ticagrelor and Venlafaxine Given Concomitantly in Healthy Subjects Aged 18 to 45 Years

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: AstraZeneca · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Study evaluates the drug-drug interaction between Ticagrelor and Venlafaxine when taken together in healthy volunteers

Conditions

• Drug Drug Interaction

Interventions

Type	Name	Description
DRUG	Ticagrelor	90 mg oral immediate release tablets, single dose on days 1 and 9
DRUG	Venlaflaxin	37.5 mg oral immediate release tablets, administered twice daily on days 4-8

Timeline

• Start date: 2011-05-01
• Primary completion: 2012-03-01
• Completion: 2012-03-01
• First posted: 2011-05-10
• Last updated: 2012-03-30

Locations

2 sites across 2 countries: United States, Sweden