NCT01347775

Inspiratory Muscle Training in Patients With End Stage Renal Failure

Inspiratory Muscle Training in Patients With End Stage Renal Failure: a Randomized Controlled Trial

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 48 (estimated)
• Sponsor: The University of Queensland · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will investigate whether inspiratory muscle training in patients with end stage renal failure can improve strength and function.

Detailed description

Patients with chronic renal failure commonly have weak respiratory muscles leading to problems in everyday activities and respiratory infections. This project aims to investigate if threshold inspiratory muscle training improves the strength, everyday function and participation of patients on haemodialysis. Forty eight patients will be recruited in a randomized controlled trial of inspiratory muscle training vs sham training. Outcome measures include the maximal inspiratory pressure and the Frenchay activities index. Initial data will be collected by a blinded assessor; the patients will train at 40 % of initial maximal inspiratory pressure for six weeks and be reassessed. If the inspiratory muscle training is effective, it will improve both the physical and functional components of the patient's lives and be recommended for all renal patients.

Conditions

• Renal Failure
• Chronic Renal Insufficiency

Interventions

Type	Name	Description
DEVICE	Inspiratory muscle training (URES HS730)	It will be set at 40% of the subjects baseline maximal inspiratory pressure and increased by 10% each week by an unblinded assistant. All subjects were trained with these devices for 8-10 breaths, 3 times a day, everyday for 6 weeks
DEVICE	Sham inspiratory muscle training (URES HS730)	Subjects in the control group underwent sham training, using the same device with the diaphragm removed, thus providing no resistance. They were not given frequency or duration but told to use the device when desired.

Timeline

• Start date: 2007-12-01
• Primary completion: 2011-12-01
• Completion: 2012-02-01
• First posted: 2011-05-04
• Last updated: 2011-05-04

Locations

1 site across 1 country: Australia