Trials / Terminated
TerminatedNCT01346579
Biomarkers in Tissue Samples From Older Women With Breast Cancer
PIK3CA Mutation Status as a Biomarker in Elderly Women With Breast Cancer
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 505 (actual)
- Sponsor
- Alliance for Clinical Trials in Oncology · Academic / Other
- Sex
- Female
- Age
- 70 Years
- Healthy volunteers
- Not accepted
Summary
This research trial studies phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA) mutation analysis in tissue samples from older patients with stage I breast cancer. Studying samples of tissue from patients with stage I breast cancer in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.
Detailed description
PRIMARY OBJECTIVES: To assess the relapse free-survival difference between patients with PIK3CA mutated and wild-type (WT) tumors and therefore validate PIK3CA mutation status as an important biomarker in women 70 years or older diagnosed with breast cancer. OUTLINE: Previously collected tissue samples are analyzed via mutation analysis of PIK3CA.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | laboratory biomarker analysis | Correlative sciences |
Timeline
- Start date
- 2011-04-01
- Primary completion
- 2014-01-01
- Completion
- 2014-01-01
- First posted
- 2011-05-03
- Last updated
- 2016-07-04
Source: ClinicalTrials.gov record NCT01346579. Inclusion in this directory is not an endorsement.