NCT01344291

Turmeric Effect on Reduction of Serum Prolactin and Related Hormonal Change and Adenoma Size in Prolactinoma Patients

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Mashhad University of Medical Sciences · Academic / Other
• Sex: Female
• Age: 20 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Prolactinoma is the most prevalent anterior hypophysis tumor. The principal treatment for this disorder is Dopamine agonist drugs including bromocriptin and Cabergoline. However, 50% of Bromocriptin treated and 17% of Cabergoline treated patients are resistant to these drugs. Curcumin is the main derivative of turmeric ,an old spice which is used frequently in Indian and Iranian cuisine. It has been proved that curcumin can reduce mammotrope cells proliferation and also intracellular hormone production. The purpose of this study is to evaluate the effect of turmeric on prolactinoma patients.

Conditions

• Hyperprolactinoma

Interventions

Type	Name	Description
DRUG	Curcumin	Curcumin is prescribed to new cases of hyperprolactinoma

Timeline

• Start date: 2011-07-01
• Primary completion: 2012-07-01
• Completion: 2012-08-01
• First posted: 2011-04-29
• Last updated: 2011-11-01

Locations

1 site across 1 country: Iran