Trials / Completed
CompletedNCT01343953
Cord Blood Transplantation in Severe Aplastic Anemia
A Prospective Phase II Study to Evaluate Cord Blood Transplantation in Inherited or Acquired Severe Aplastic Anemia Refractory or in Relapse After Immunosuppressive Therapy
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 26 (estimated)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Academic / Other
- Sex
- All
- Age
- 3 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
This is a Prospective Phase II Study to evaluate Cord Blood Transplantation in Inherited or Acquired Severe Aplastic Anemia Refractory or in Relapse after Immunosuppressive Therapy in the absence of an HLA identical donor;
Detailed description
This is a Prospective Phase II Study to evaluate Cord Blood Transplantation in Inherited or Acquired Severe Aplastic Anemia Refractory or in Relapse after Immunosuppressive Therapy in the absence of an Human Leucocyte Antigen (HLA) identical donor; 26 patients will be recruited, according to a one step Fleming design
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Cord Blood Transplantation | One or 2 cord blood units containing alone or both together more than 4x107 frozen nucleated cells/Kg with no more than 2 out of 6 HLA mismatches between them and with the patients for acquired Severe Aplastic Anemia |
Timeline
- Start date
- 2011-05-01
- Primary completion
- 2017-06-01
- Completion
- 2017-06-01
- First posted
- 2011-04-28
- Last updated
- 2017-06-15
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT01343953. Inclusion in this directory is not an endorsement.