NCT01343420

Dog Hair Extract Study

Dog Hair Evaluation Potency by Prick Skin Testing

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: National Jewish Health · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Liquid allergen extracts contain proteins, such as (but not limited to) tree, weed, cat, cockroach, and nuts, and are used to identify allergies by observing the body's reaction to the introduction of extract underneath the skin. There are a few dog allergen extracts commercially available in the US for allergy testing; however, none of these products are standardized, meaning they are not required to be the same strength. Because some extracts are not as potent (strong) as others, it's possible that some patients' allergies are misdiagnosed. Typically, the most potent (strong), but safe extract should be used so that allergic patients are correctly diagnosed. The purpose of this study is to compare the safety and potency of an investigational (not approved for use by the United States Food and Drug Administration \[FDA\]) dog allergen extract with two commercially available dog extracts, which are of differing potencies.

Detailed description

This study is designed to assess the potency of a modified dog hair and dander extract in comparison with the two commercially available dog hair and dander extracts. This is a pilot study to estimate a target strength of dog extract in order to proceed to further studies.

Conditions

• Potency of Dog Hair Extract

Interventions

Type	Name	Description
BIOLOGICAL	Dog Hair Extract, ALK-Abelló, Inc.	ALK-Abelló dog epithelial 1:10w/v glycerin

Timeline

• Start date: 2010-11-01
• Primary completion: 2011-10-01
• Completion: 2011-10-01
• First posted: 2011-04-28
• Last updated: 2021-01-19

Locations

1 site across 1 country: United States