NCT01341756

Palliative Radiotherapy for Symptomatic Locally Advanced Gastric Cancer: A Phase II Trial

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 63 (estimated)
• Sponsor: National University Hospital, Singapore · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

The hypothesis of this study is that a radiotherapy dose of 36Gy in 12 fractions, which equates to a BED of 48.6Gy, increases the response rates of symptom relief compared to historical controls.

Detailed description

The hypothesis of this study is that a radiotherapy dose of 36Gy in 12 fractions, which equates to a BED of 48.6Gy, increases the response rates of symptom relief compared to historical controls. (Tey et al.) With this dose fractionation is used for bleeding, there is an increase in response rates from 55%(historical) to 75%for pain, there is an increase in response rates from 25% (historical) to 45% for obstruction, there is an increase in response rates from 25% (historical) to 45%

Conditions

• Gastric Cancer

Interventions

Type	Name	Description
RADIATION	Palliative Radiotherapy	Palliative Radiotherapy to a total dose of 36Gy in 12 fractions

Timeline

• Start date: 2009-07-01
• Primary completion: 2011-07-01
• Completion: 2012-07-01
• First posted: 2011-04-26
• Last updated: 2011-05-09

Locations

1 site across 1 country: Singapore