Trials / Completed
CompletedNCT01340378
A Pilot Study of Thrombin Generation Changes in Neonates Undergoing Placement of a Blalock-Taussig Shunt
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (actual)
- Sponsor
- Emory University · Academic / Other
- Sex
- All
- Age
- 30 Days
- Healthy volunteers
- Not accepted
Summary
The primary goal of this investigation is to describe perioperative thrombin generation in neonates undergoing placement of a Blalock-Taussig (BT) shunt to better understand the coagulation changes that precipitate postoperative shunt occlusion.
Detailed description
To accomplish our goal, the investigators will measure preoperative levels of one major procoagulant (prothrombin) and one major anticoagulant (Antithrombin). The investigators will also measure preoperative and postoperative thrombelastograms (TEG) and preoperative and postoperative thrombin generation curves (TGC).
Conditions
Timeline
- Start date
- 2010-01-01
- Primary completion
- 2013-01-01
- Completion
- 2014-12-01
- First posted
- 2011-04-22
- Last updated
- 2014-12-12
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01340378. Inclusion in this directory is not an endorsement.