NCT01337635

Vitamin D Deficiency and Atopic Dermatitis

Treatment Of Vitamin D Deficiency And Effect On Atopic Dermatitis Severity

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 7 (actual)
• Sponsor: Medical College of Wisconsin · Academic / Other
• Sex: All
• Age: 1 Year – 18 Years
• Healthy volunteers: Not accepted

Summary

Atopic dermatitis is a chronic skin disease characterized by a defective skin barrier, inflammation, and increased propensity for skin infections. Vitamin D is a fat-soluble vitamin that is primarily acquired through local production in the skin after ultraviolet light exposure but can also be obtained through natural and supplemental dietary sources. This randomized controlled trial will examine the effects of vitamin D repletion on atopic dermatitis severity in patients with diagnosed deficiency. The investigators hypothesize that pediatric patients with moderate or severe atopic dermatitis and vitamin D deficiency will have improved cutaneous disease after treatment with high dose as compared to standard dose vitamin D.

Conditions

• Atopic Dermatitis
• Vitamin D Deficiency

Interventions

Type	Name	Description
DRUG	Vitamin D	Ergocalciferol 300,000 IU single oral dose Cholecalciferol 400 IU orally every day for 6 weeks

Timeline

• Start date: 2010-11-01
• Primary completion: 2012-12-01
• Completion: 2013-04-01
• First posted: 2011-04-19
• Last updated: 2018-12-05
• Results posted: 2015-04-08

Locations

1 site across 1 country: United States