Clinical Trials Directory

Trials / Completed

CompletedNCT01335347

Safety Study of an Oral Vaccine to Prevent Avian Influenza

A Dose Escalation Phase 1 Safety and Immunogenicity Study of an Oral Viral Vector Vaccine Encoding Avian Influenza H5N1 Hemagglutinin Protein and dsRNA Adjuvant in Healthy Adults

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
54 (actual)
Sponsor
Vaxart · Industry
Sex
All
Age
18 Years – 49 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to demonstrate the safety and immunogenicity of an oral vaccine to prevent avian influenza. Volunteers will receive either one or two doses of research vaccine or placebo as part of this study.

Conditions

Interventions

TypeNameDescription
BIOLOGICALND1.1adenovirus with the dsRNA adjuvant, dried and put into capsules
BIOLOGICALPlacebo controlCapsules of the same size and shape as experimental groups

Timeline

Start date
2011-04-01
Primary completion
2012-08-01
Completion
2012-09-01
First posted
2011-04-14
Last updated
2013-01-03

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01335347. Inclusion in this directory is not an endorsement.