NCT01334619

Ropivacaine Volume for Ultrasound-guided Retrograde Infraclavicular Brachial Plexus Block

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Beijing Jishuitan Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The retrograde infraclavicular brachial plexus block has been proved an effective and safe approach. Realtime ultrasound guide will facilitate a successful peripheral nerve block. The purpose of this study was to determine the medium effective volume required to produce an effective retrograde infraclavicular block using an ultrasound (US)-guided technique.

Detailed description

Thirty adults undergoing elective upper limb surgery received an US-guided retrograde infraclavicular block. The initial concentration of 0.5% ropivacaine injected was 30 ml, which was subsequently varied at a ratio of 1: 1.2 for each consecutive patient according to the response of the previous patient. The medium effective volume (EV50) was determined using the Dixon and Massey up-and-down method. The effective volume in 95% of patients (EV95) was calculated using probit regression.

Conditions

• Upper Extremity Injury Trauma

Interventions

Type	Name	Description
PROCEDURE	appropriate volume of 0.5% ropivacaine	initial concentration: 30 ml, subsequently varied at a ratio of 1: 1.2 for each consecutive patient according to the response of the previous patient, until 5 up-and-down cycles completed.

Timeline

• Start date: 2010-03-01
• Primary completion: 2010-04-01
• Completion: 2010-05-01
• First posted: 2011-04-13
• Last updated: 2011-04-13

Locations

1 site across 1 country: China