NCT01328678

A Study of Vitamin D in Subjects With Alopecia Areata

A Pilot Study of Vitamin D in Subjects With Alopecia Areata

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 10 (actual)
• Sponsor: Avera McKennan Hospital & University Health Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to assess the parathyroid-vitamin D-calcium axis in subjects with alopecia areata. The hypothesis behind this study is that hypovitaminosis D might contribute to the pathogenesis of alopecia areata.

Detailed description

Alopecia Areata (AA) is a T-Cell mediated, non-scarring, polygenic, autoimmune disease of the hair follicle. It has been reported to be associated with other autoimmune diseases, especially autoimmune thyroid disease and vitiligo. It is more common in females. Recently, vitamin D deficiency has been claimed to contribute to the pathogenesis of multiple autoimmune disease. There is a strong inverse correlation between the level of 25-hydroxyvitamin D levels and the autoimmune disease in adolescents.

Conditions

• Alopecia Areata

Timeline

• Start date: 2009-08-01
• Primary completion: 2011-07-01
• Completion: 2011-07-01
• First posted: 2011-04-05
• Last updated: 2011-07-08

Locations

1 site across 1 country: United States