NCT01328132

Effect of Hyperoncotic Albumin on Vascular Hemodynamics and Oxygen Delivery Following Orthotopic Liver Transplant

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The primary aim of this study is to assess the effect of hyperoncotic albumin on vascular hemodynamics and oxygen delivery after orthotopic liver transplant. The secondary aim is to try to identify the dominant physiological mechanism so that we will be able to better identify patients that may benefit from the use of albumin (25%) boluses in addition to standard care in patients following liver transplantation.

Conditions

• Other Complications of Liver Transplant

Interventions

Type	Name	Description
DRUG	Saline	100 ml of saline will be given in addition to the standard of care every 8 hours for 24 hours.
DRUG	25% albumin	100 ml of 25% albumin will be given in addition to the standard of care every 8 hours for 24 hours

Timeline

• Start date: 2011-03-01
• Primary completion: 2011-10-01
• Completion: 2011-10-01
• First posted: 2011-04-04
• Last updated: 2011-04-04

Locations

1 site across 1 country: Canada