NCT01327430

Phospholipid Absorption of a Milk Phospholipid

Effect of a Milk Phospholipid Supplementation on the Lipid Metabolism in Healthy Volunteers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: University of Jena · Academic / Other
• Sex: Female
• Age: 30 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to investigate parameters of the lipid metabolism in plasma and feces of healthy subjects after a dietary supplementation of different dosages of milk phospholipids.

Detailed description

To date the mechanisms for the intestinal absorption of glycerophosphates and sphingolipids are not completely investigated. It is assumed, that sphingolipids and sterols compete for intestinal absorption. In addition it is unclear, if a dietary phospholipid supplementation may influence the phospholipid concentration in plasma. To evaluate the effect of a dietary phospholipid supplementation 15 healthy female subjects received over 10 days daily 3 g of milk phospholipids stirred in a dairy product. During the following 10 days the subjects were supplemented with daily 6 g milk phospholipid. Finally, the subjects received over 10 days 6 g of the milk phospholipid in a dairy product and 2 g of plant sterols serving a commercial product.

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Milk phospholipid	During day 1 until 10 the subjects were supplemented with daily 3 g milk phospholipids, during the day 11 and 20 the supplementation was increased to daily 6 g, and during the day 21 and 30 the subjects received daily 6 g milk phospholipids and 2 g of plant sterols.

Timeline

• Start date: 2010-05-01
• Primary completion: 2010-06-01
• Completion: 2010-06-01
• First posted: 2011-04-01
• Last updated: 2011-04-01

Locations

1 site across 1 country: Germany