Trials / Completed
CompletedNCT01324895
Retrospective Analysis of Treatment Outcomes in Patients With Bacterial Overgrowth Syndrome Diagnosed by D-Xylose Breath Testing
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 944 (actual)
- Sponsor
- University of Florida · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
The objective of this study is to compare the efficacy of prokinetics versus antibiotics versus a combination of antibiotics plus prokinetics in the eradication of Small-Intestinal Bacterial Over-Growth Syndrome (SIBO) in those with and without a positive D-xylose Breath Test. Hypothesis: Patients with SIBO treated with a combination of prokinetics and in particular octreotide and antibiotics will have reduced recurrence rates of SIBO than either therapy given alone.
Detailed description
We want to determine whether treatment with prokinetics such as Octreotide, Azithromycin, Erythromycin or Tegaserod alone, versus antibiotics alone, or combination of antibiotics plus prokinetics results in symptomatic improvement in patients with SIBO (defined by a positive D xylose Breath test).
Conditions
- Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
- Small Bowel Bacterial Overgrowth Syndrome (SBBOS)
Timeline
- Start date
- 2010-08-01
- Primary completion
- 2012-03-01
- Completion
- 2012-03-01
- First posted
- 2011-03-29
- Last updated
- 2012-03-26
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01324895. Inclusion in this directory is not an endorsement.