Trials / Completed
CompletedNCT01321021
Influence of Losartan and Diphenhydramine on Emotional and Cognitive Functions in Healthy Human Subjects
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 80 (actual)
- Sponsor
- Prof. Dominique de Quervain, MD · Academic / Other
- Sex
- All
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
This project aims at identifying novel pharmacological targets for the treatment of memory disorders.
Detailed description
To investigate the effects of the histamine H1 receptor antagonist diphenhydramine and the angiotensin II receptor antagonist losartan on emotional and cognitive functions in healthy human subjects.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Losartan, Diphenhydramine, Placebo | placebo controlled crossover study with two arms: Losartan 40mg, Diphenhydramine 40mg |
Timeline
- Start date
- 2011-03-01
- Primary completion
- 2011-07-01
- Completion
- 2011-08-01
- First posted
- 2011-03-23
- Last updated
- 2012-05-03
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT01321021. Inclusion in this directory is not an endorsement.