NCT01319747

Video-Assisted Thoracoscopic Pulmonary Vein Isolation Versus Percutaneous Catheter Ablation in Atrial Fibrillation Trial

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 77 (actual)
• Sponsor: Medisch Spectrum Twente · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Recent studies demonstrated that radiofrequency isolation of the pulmonary veins (PVI) and surgically video assisted thorascopic pulmonary vein isolation (VATS-PVI) are acceptable or even superior alternatives to antiarrhythmic drug therapy in patients with symptomatically paroxysmal atrial fibrillation (AF). However, data comparing effectiveness in both interventions are limited. The investigators want to compare the effectiveness of PVI and VATS-PVI. Secondary objectives are to compare the duration of hospitalization, quality of Life, cost and to compare the satisfaction of the patients.

Conditions

• Atrial Fibrillation

Interventions

Type	Name	Description
PROCEDURE	PVI	For catheter ablation, we used irrigated 4mm RF-ablation catheters, at a maximum power of 30-35Watt, an irrigation rate of 20 mL/min. PV isolation was performed by wide circumferential ablation, encircling all ipsilateral PVs.
PROCEDURE	VATS-PVI	A bilateral video-assisted thoracoscopic (VATS) pulmonary vein isolation and left atrial appendage (LAA) excision is performed under general anaesthesia and double-lumen endotracheal ventilation.

Timeline

• Start date: 2010-09-01
• Primary completion: 2013-11-01
• Completion: 2014-11-01
• First posted: 2011-03-22
• Last updated: 2024-11-22

Locations

1 site across 1 country: Netherlands