NCT01319682

The Effect of Intravenous Lidocaine on Pain After Lumbar Spinal Fusion

Intravenous Lidocaine for Effective Pain Relief After Posterior Lumbar Spinal Fusion: a Prospective, Randomized, Double-blind, Placebo-controlled Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: Chung-Ang University Hosptial, Chung-Ang University College of Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

This prospective randomized study aims to evaluate the effectiveness of intravenous lidocaine injection on the relief of pain in patients undergoing 1-level posterior lumbar fusion. A total of 54 patients will be randomized into one of two groups (group C or group I) based on Excel number generation. Patients in group C will receive received normal saline intravenous injection, and patients in group I will receive an intravenous bolus injection of 1.5 mg/kg lidocaine followed by a continuous lidocaine infusion of 2 mg/kg/hr. Visual analogue scale pain scores, fentanyl consumption and the frequency at which patients pushed the button (FPB) of a patient-controlled analgesia system will be recorded at 4, 12, 24, 48 hours postoperatively.

Conditions

• Postoperative Pain

Interventions

Type	Name	Description
DRUG	Intravenous lidocaine injection	Patients in Group I (intravenous lidocaine injection group) received an intravenous bolus injection of 1.5 mg/kg lidocaine followed by a continuous lidocaine infusion of 2 mg/kg/hr.
DRUG	Intravenous normal saline injection	The patients in Group C (placebo control group) received normal saline intravenous injection

Timeline

• Start date: 2011-03-01
• Primary completion: 2013-02-01
• Completion: 2013-02-01
• First posted: 2011-03-22
• Last updated: 2013-08-02

Locations

1 site across 1 country: South Korea