Trials / Terminated
TerminatedNCT01319526
Biomarkers in Blood Samples From Patients With HIV Infection and Stage III or Stage IV Hodgkin Lymphoma Undergoing Chemotherapy
Quantification of HIV-1 Reservoirs in HIV-Positive Persons Receiving Response-Adapted Therapy for Stage III-IV Hodgkin Lymphoma: A Companion Protocol to SWOG Protocol S0816 (AMC-073)
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 1 (actual)
- Sponsor
- AIDS Malignancy Consortium · Network
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
RATIONALE: Studying samples of blood in the laboratory from patients undergoing treatment with HIV infection and Hodgkin lymphoma may help doctors learn more about the effects of therapy on HIV. PURPOSE: This research study is studying biomarkers in blood samples from patients with HIV infection and stage III or stage IV Hodgkin lymphoma undergoing chemotherapy.
Detailed description
OBJECTIVES: Primary * To quantify HIV-1 persistence in prospectively collected samples from patients on suppressive antiretroviral therapy undergoing chemotherapy for Hodgkin lymphoma. OUTLINE: This is a multicenter study. Blood samples are collected before, during, and after treatment for lymphoma for HIV-1 RNA levels using standard and single copy assays and HIV-1 DNA quantification (peripheral blood mononuclear cells). After completion of treatment, patients are followed up periodically for up to 2 years.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | DNA analysis | |
| GENETIC | RNA analysis | |
| OTHER | laboratory biomarker analysis |
Timeline
- Start date
- 2011-06-01
- Primary completion
- 2013-01-01
- Completion
- 2013-01-01
- First posted
- 2011-03-21
- Last updated
- 2020-07-29
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT01319526. Inclusion in this directory is not an endorsement.