NCT01318681

Rhinitis, Cognition and Driving Performance

Effects of Treated and Untreated Allergic Rhinitis on Mood, Cognitive Functions and Actual Driving Performance

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Maastricht University Medical Center · Academic / Other
• Sex: All
• Age: 21 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This study investigates the effects of Allergic Rhinitis (AR) on driving ability and memory functions. Our group has previously shown that patients suffering from AR symptoms perform less well on tasks requiring sustained attention compared to non symptomatic controls. Car driving is a typical behavior that is susceptible for changes in sustained attention and might therefore become worse under conditions when patients suffer from AR symptoms. We will compare the driving performance of untreated, symptomatic AR patients with the performance of symptomatic patients that have been treated with either a systemic AR medication (a pill) or a topical medication (nasal spray)

Conditions

• Seasonal Allergic Rhinitis
• Driving Ability
• Cognition

Interventions

Type	Name	Description
DRUG	cetirizine 10 mg	cetirizine 10 mg over encapsulated
DRUG	fluticasone furoate	nasal spray 25ug per dose
DRUG	placebo	a placebo nasal spray and placebo capsule are available for double dummy treatment

Timeline

• Start date: 2011-01-01
• Primary completion: 2012-03-01
• Completion: 2012-10-01
• First posted: 2011-03-18
• Last updated: 2013-11-08

Locations

1 site across 1 country: Netherlands