NCT01315704

Alzheimer's Disease and Related Disorders

Maladie d'Alzheimer et Maladies apparentées : Caractérisation Des Anomalies Cognitivo-motrices, et Des Effets Des médicaments Anti-démence et de la Vitamine D à Partir de la Mise en Place d'Une Base de données au CMRR du CHU d'Angers

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 700 (estimated)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The purpose of this study is to compare characteristics of gait and balance measured among patients with Alzheimer's disease or related disorders separated into 3 groups according to the stage of disease (i.e., pre-dementia, mild and moderate dementia stages); to determine the effects of anti-dementia drugs and vitamin D on cognitive motor abnormalities; and to establish a database at Angers University Memory Centre.

Detailed description

Although gait disorders are frequently associated with Alzheimer's disease and related disorders (ADRD), few studies have focused on cognitive motor effects of anti-dementia drugs and vitamin D. The objectives of this study are to * Compare characteristics of gait and balance measured among patients with ADRD separated into 3 groups according to stages of disease (i.e., pre-dementia, mild and moderate dementia stages) * To determine the effects of anti-dementia drugs and vitamin D on cognitive motor abnormalities * To determine whether motor abnormalities could be associated with cognitive impairments, specifically executive dysfunctions * To establish a database at Angers University Memory Center.

Conditions

• Alzheimer's Disease
• Gait Apraxia
• Impaired Cognition

Interventions

Type	Name	Description
DRUG	Drug intervention	before-after interventional (anti-dementia drugs and/or vitamin D) study

Timeline

• Start date: 2009-11-01
• Primary completion: 2017-11-01
• Completion: 2017-11-01
• First posted: 2011-03-15
• Last updated: 2011-03-15

Locations

1 site across 1 country: France